![]() The first hydroxylation of ergocalciferol takes place in the liver (to 25-hydroxyvitamin D) and the second in the kidneys (to 1, 25-dihydroxyvitamin D). The in vivo synthesis of the major biologically active metabolites of vitamin D occurs in two steps. Inactive Ingredients: FD&C Blue #1, FD&C Yellow #5, Gelatin, Glycerin, Soybean Oil. One USP unit of vitamin D 2 is equivalent to one International Unit (IU), and 1 mcg of vitamin D 2 is equal to 40 IU.Įach capsule contains 1.25 mg (50,000 International Units vitamin D) of ergocalciferol, USP, in an edible vegetable oil.Įrgocalciferol, also called vitamin D 2, is 9, 10-secoergosta-5,7,10 (19), 22-tetraen-3-ol, (3ß,5Z,7E, 22 E)- (C 2 8H 4 4O) with a molecular weight of 396.65, and has the following structural formula: There are more than 10 substances belonging to a group of steroid compounds, classified as having vitamin D or antirachitic activity. Ergosterol or provitamin D 2 is found in plants and yeast and has no antirachitic activity. Drisdol brand of ergocalciferol capsules, USP, is a synthetic calcium regulator for oral administration.Įrgocalciferol is a white, colorless crystal, insoluble in water, soluble in organic solvents, and slightly soluble in vegetable oils.
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